Successful treatment of inverted Takotsubo cardiomyopathy after severe traumatic brain injury with milrinone after dobutamine failure
| Autor: | Timothée Abaziou, Rémi Menut, Mohamed Srairi, Clément Delmas, Fouad Marhar, François Gaussiat, Olivier Fourcade, Claire Larcher, Ségolène Mrozek, Thomas Geeraerts, Vincent Atthar |
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| Rok vydání: | 2016 |
| Předmět: |
Pulmonary and Respiratory Medicine
Inotrope medicine.medical_specialty Cardiotonic Agents Adolescent Cardiomyopathy Cardiac index 030204 cardiovascular system & hematology Critical Care and Intensive Care Medicine 03 medical and health sciences 0302 clinical medicine Takotsubo Cardiomyopathy Dobutamine Internal medicine Brain Injuries Traumatic medicine Humans Treatment Failure Trauma Severity Indices business.industry Hemodynamics Levosimendan medicine.disease Anesthesia Shock (circulatory) Cardiology Milrinone Female medicine.symptom Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Heart & Lung. 45:406-408 |
| ISSN: | 0147-9563 |
| DOI: | 10.1016/j.hrtlng.2016.06.007 |
| Popis: | Background Takotsubo cardiomyopathy can occur at the early phase of severe acute brain injuries. In the case of cardiac output decrease or shock, the optimal treatment is still a matter of debate. Due to massive stress hormone release, the infusion of catecholamines may have limited effects and may even aggravate cardiac failure. Other inotropic agents may be an option. Levosimendan has been shown to have potential beneficial effects in this setting, although milrinone has not been studied. Methods We report a case of a young female presenting with inverted Takotsubo cardiomyopathy syndrome after severe traumatic brain injury. Results Due to hemodynamic instability and increasing levels of infused norepinephrine, dobutamine infusion was begun but rapidly stopped due to tachyarrhythmia. Milrinone infusion stabilized the patient's hemodynamic status and improved cardiac output without deleterious effects. Conclusion Milrinone could be a good alternative when inotropes are required in Takotsubo cardiomyopathy and when dobutamine infusion is associated with tachyarrhythmia. |
| Databáze: | OpenAIRE |
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