Combining reconstructive and ablative surgical treatment of chronic breast cancer-related lymphedema (BCRL): safe and effective

Autor: Alina A. Ghazaleh, Tristan M. Handschin, Julia Buckowiecki, Frédérique S. Chammartin, Christoph Andree, Dirk J. Schaefer, Martin Haug, Elisabeth A. Kappos, Katrin Seidenstuecker
Rok vydání: 2022
Předmět:
Zdroj: Breast cancer research and treatment. 197(1)
ISSN: 1573-7217
Popis: Purpose We investigated whether a one-stage combination of vascularized lymph node transfer (VLNT) with water jet-assisted liposuction (WAL) can be safely performed and results in improved patient outcomes such as a greater reduction in arm volume when treating chronic breast cancer-related lymphedema (BCRL). Methods In this retrospective cohort study, we included all patients from our encrypted lymphedema database treated for chronic BCRL with VLNT or VLNT + WAL who had a minimum follow-up of two years. We analyzed patient-specific variables including arm circumferences as well as patient-reported outcomes before and after surgery as well as surgery time, surgery-related complications and patient satisfaction. Results Only the mean preoperative differences of the circumferences between the lymphedematous and the unaffected arm in individual patients showed a statistically significant difference between treatment groups (p p p = 0.323). Conclusions Our findings suggest that a one-stage combination of VLNT with WAL does not result in more complications even though it also entails a longer surgery time. This is acceptable as secondary interventions resulting in overall longer surgery times and higher costs can be avoided. A one-stage combination might be especially favourable for patients suffering from more severe chronic BCRL.
Databáze: OpenAIRE