Dual Pulmonary Infection with Mycobacterium tuberculosis and Pneumocystis carinii in Patients Infected with Human Immunodeficiency Virus
| Autor: | Ranmini Kularatne, Vivian Ferraz, Dragana Orlovic, Raymond A. Smego |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Male Microbiology (medical) medicine.medical_specialty Tuberculosis Opportunistic infection AIDS-Related Opportunistic Infections Antitubercular Agents Gastroenterology Mycobacterium tuberculosis South Africa Adrenal Cortex Hormones Internal medicine HIV Seropositivity Humans Multicenter Studies as Topic Medicine Tuberculosis Pulmonary Retrospective Studies L-Lactate Dehydrogenase biology Pneumocystis business.industry Pneumonia Pneumocystis Respiratory disease Sputum medicine.disease biology.organism_classification Anti-Bacterial Agents Pneumonia Infectious Diseases Pneumocystis carinii Immunology Drug Therapy Combination Female medicine.symptom business |
| Zdroj: | Clinical Infectious Diseases. 32:289-294 |
| ISSN: | 1537-6591 1058-4838 |
| DOI: | 10.1086/318475 |
| Popis: | During a 22-month period, we identified 39 patients with human immunodeficiency virus (HIV) infection (mean CD4(+) count, 90 cells/mm(3)) who were hospitalized with pneumonia and who had sputum and/or other specimens that tested concurrently positive for both Mycobacterium tuberculosis and Pneumocystis carinii. The most common chest x-ray abnormality was a reticulonodular pattern or bilateral infiltrates (n=26). Serum lactate dehydrogenase levels were elevated in 17 (85%) of 20 of patients tested (mean value, 2208 U/L). Mean O(2) saturation and PO(2) were 89% and 64 mm Hg, respectively. A majority (24 patients [62%]) received both antituberculous and anti-PCP therapy (17 with steroids), and 22 improved. All ten patients who received no treatment for PCP improved and were discharged from the hospital, whereas 4 (80%) of the 5 persons who received no antituberculous treatment had a poor outcome (P |
| Databáze: | OpenAIRE |
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