Photocycloaddition of chalcones to yield cyclobutyl ditopic cyclophanes

Autor:	Giancarlo Doddi, Nicoletta Di Bello, Vincenzo Fares, Paolo Mencarelli, Francesca R Cibin, Elio Ullucci
Rok vydání:	2003
Předmět:	Cyclobutanes photochemistry chalcones Stereochemistry carbocycles Organic Chemistry Ring (chemistry) enones Biochemistry Cycloaddition chemistry.chemical_compound chemistry Intramolecular force Yield (chemistry) Drug Discovery cyclophanes cycloaddition photocyclization Cyclophane
Zdroj:	Tetrahedron. 59:9971-9978
ISSN:	0040-4020
DOI:	10.1016/j.tet.2003.10.026
Popis:	The intramolecular photocycloaddition of chalcones to give cyclobutanes has proved to be a fast and convenient method to shrink a cyclophane ring to a tricyclic system, in order to prepare potential ditopic receptors. X-Ray results confirm the previously indicated structure for the cyclobutanes 2a (n=1, m=1), in which the cyclization occurs by a head-to-head syn ring closure. NMR results indicate that the same process occurs for the cyclobutanes 2b (n=2, m=2) and 2c (n=1, m=3).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d27d68b826bd1c5728a50d35ab4bb1 https://doi.org/10.1016/j.tet.2003.10.026 Zobrazit plný text záznamu Full Text from ScienceDirect