Urinary retention--an unusual dystonic reaction to continuous metoclopramide infusion
| Autor: | Alan W. Craft, Andrew D.J. Pearson, Mudra Kohli-Kumar, Ian Sharkey |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Metoclopramide Priapism 030226 pharmacology & pharmacy Loading dose 03 medical and health sciences 0302 clinical medicine Rhabdomyosarcoma medicine Humans Pharmacology (medical) General Pharmacology Toxicology and Pharmaceutics Adverse effect Infusions Intravenous Slurred speech 030109 nutrition & dietetics business.industry Urinary retention Procyclidine Prostatic Neoplasms Urinary Retention medicine.disease Surgery Dystonia Anesthesia Child Preschool Vomiting medicine.symptom business medicine.drug |
| Zdroj: | DICP : the annals of pharmacotherapy. 25(5) |
| ISSN: | 1042-9611 |
| Popis: | Vomiting is one of the most distressing adverse effects of cancer chemotherapy. Metoclopramide by continuous infusion (400 μg/kg/h after a loading dose of 2.5 mg/kg) is a novel administration method for optimizing efficacy. A two-year-old boy developed urinary retention on three occasions, once accompanied by priapism and slurred speech, while receiving a continuous infusion. This was reversed by procyclidine, suggesting that it may have been a dystonic reaction. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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