The Clinician as Investigator
| Autor: | Robert L. Frye, Mary M. Hand, Robyn J. Barst, Marcus Flather, Christopher P. Cannon, L. Kristin Newby, E. Magnus Ohman, Robert L. Jesse, Frans Van de Werf, Daniel P. Sulmasy, Ellis Lader, Fernando Ferreira Costa, Joan M. Fair, Jane E. Freedman |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Clinical Trials as Topic
Medical education Evidence-Based Medicine Practice setting business.industry MEDLINE Private Practice Evidence-based medicine Choice Behavior Research Personnel law.invention Clinical trial Randomized controlled trial law Private practice Physiology (medical) Workforce Humans Medicine Clinical Medicine Physician's Role Cardiology and Cardiovascular Medicine business Randomized Controlled Trials as Topic |
| Zdroj: | Circulation. 109:2672-2679 |
| ISSN: | 1524-4539 0009-7322 |
| Popis: | The rapid development of new drugs, therapies, and devices has created a dramatic increase in the number of trials needed to properly evaluate them. The majority of patients treated today, many of whom could be eligible for participation in these studies, are seen in community hospitals and medical practices that are not affiliated with an academic medical center. Thus, there is a demonstrable need for physicians in private practice to enlist as investigators in these trials. This article is intended to encourage those physicians by describing the need and providing the rationale for their participation. It covers basic requirements for participating in clinical trials and outlines ethical, regulatory, financial, and other logistical issues of importance for the potential investigator and provides an algorithm for selecting a study for participation. Finally, the appendices review basic elements of study design and statistical principles, which may be of interest to a potential investigator. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|