Age-Dependent Trends in the Celiac Disease: A Tertiary Center Experience
| Autor: | Alexander Krauthammer, Luba Marderfeld, Yael Mozer-Glassberg, Noam Zevit, Raanan Shamir, Ari Silbermintz, Manar Matar, Vered Nachmias Friedler, Orith Waisbourd-Zinman, Amit Assa, Michal Rozenfeld Bar Lev, Anat Guz-Mark |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Anemia Disease 03 medical and health sciences Diet Gluten-Free 0302 clinical medicine Weight loss 030225 pediatrics Internal medicine medicine Humans Hypoalbuminemia Israel Child Aged Autoantibodies Retrospective Studies Transglutaminases business.industry Medical record Gastroenterology medicine.disease Diarrhea Celiac Disease Pediatrics Perinatology and Child Health Cohort Vomiting 030211 gastroenterology & hepatology medicine.symptom business |
| Zdroj: | Journal of pediatric gastroenterology and nutrition. 72(6) |
| ISSN: | 1536-4801 |
| Popis: | OBJECTIVES Celiac disease (CD) is a common intestinal autoimmune disorder with diverse presenting features. We aimed to determine age-dependent patterns in CD presentation, diagnosis and management at a large tertiary referral center. METHODS A retrospective review of electronic medical records of pediatric patients diagnosed with CD between January 1999 and December 2018 at Schneider Children's Medical Center of Israel. We compared demographics, clinical and laboratory parameters between four age groups at CD presentation. RESULTS A cohort of 932 children was divided into four groups by age (in years) at diagnosis: 0-3 (17.9%), 3-6 (31.8%), 6-12 (34.5%), 12-18 (15.8%). The youngest age group presented more frequently with diarrhea, weight loss, abdominal distention, vomiting and lower weight z scores, P |
| Databáze: | OpenAIRE |
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