Mean Platelet Volume (MPV) as an inflammatory marker in type 2 diabetes mellitus and obesity
| Autor: | Gulali Aktas, Tuba Taslamacioglu Duman, Mustafa Sit, Burcin M. Atak, Mehmet Zahid Kocak, Haluk Savli, Edip Erkus |
|---|---|
| Přispěvatelé: | BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Aktaş, Gülali, Koçak, Mehmet Zahid, Duman, Tuba Taslamacıoğlu, Erkuş, Edip, Atak, Burçin Meryem |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
lcsh:Medicine 030209 endocrinology & metabolism Gastroenterology Body Mass Index 03 medical and health sciences 0302 clinical medicine Internal medicine Inflammatory marker medicine Obesity Mean platelet volume Inflammation lcsh:R5-920 business.industry lcsh:R Type 2 Diabetes Mellitus General Medicine medicine.disease type 2 diabetes mellitus body mass index obesity mean platelet volume inflammation 030220 oncology & carcinogenesis lcsh:Medicine (General) business Mean Platelet Volume |
| Zdroj: | Bali Medical Journal, Vol 7, Iss 3 (2018) |
| ISSN: | 2302-2914 2089-1180 |
| DOI: | 10.15562/bmj.v7i3.806 |
| Popis: | Background: Type 2 diabetes mellitus and obesity are two important disorders which are associated with the enormous amount of morbidity and mortality. Inflammation plays a crucial role in development and complications of these diseases. Aim: We aimed to compare mean platelet volume (MPV) as an inflammatory marker in well and poorly controlled type 2 diabetic subjects and to observe its association with obesity indices, body mass index (BMI) and waist circumference. Method: Data of type 2 diabetic patients obtained from institutional database retrospectively analyzed. Patients were divided into two groups according to the HbA1c level as follows: HbA1c lower than 7% were classified as well-controlled, and HbA1c equal to or greater than 7% were classified as poorly controlled diabetics. Result: Both MPV, body mass index (BMI) and waist circumference were significantly higher in poorly controlled diabetics compared to patients with well-controlled type 2 DM. Conclusion: MPV could be considered as a marker of inflammatory burden in type 2 DM and obesity. Due to its cost-effective and easy to assess nature, MPV may be screened periodically in these patients, along with HbA1c and other measures to keep both physicians and patients aware of the inflammatory load of these diseases. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|