Encapsulation-release property of amphiphilic hyperbranched d-glucan as a unimolecular reverse micelle
| Autor: | Noriaki Kaneko, Hirofumi Tani, Toyoji Kakuchi, Atsushi Narumi, Masaki Tamaki, Tomoko Imai, Yoshikazu Kitajyo, Yoko Sakai, Harumi Kaga, Kenji Takahashi, Toshifumi Satoh |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
chemistry.chemical_classification
Polymers and Plastics Organic Chemistry Ethyl acetate Thymol blue Micelle Hydrolysis chemistry.chemical_compound End-group chemistry Polymer chemistry Unimolecular reverse micelle Materials Chemistry Rose bengal Amphiphilic hyperbranched polymer Encapsulation Solubility Glucan |
| Zdroj: | Polymer. 48(5):1237-1244 |
| ISSN: | 0032-3861 |
| Popis: | The synthesis of a novel unimolecular reverse micelle, the hyperbranched d -glucan carbamate ( 3 ), was accomplished through the carbamation reaction of the hyperbranched d -glucan ( 1 ) with the N -carbonyl l -leucine ethyl ester ( 2 ) in pyridine at 100 °C. Polymer 3 was soluble in a large variety of organic solvents, such as methanol, acetone, chloroform, and ethyl acetate, and insoluble in water, which remarkably differed from the solubility of 1 . The degree of carbamate substitution (DS) for 3 was controlled by the feed rate of 2 , and the DS values were in the range of 46.0–93.7%. Polymer 3 possessed the encapsulation ability for water-soluble molecules, such as rose bengal, thymol blue, and alizarin yellow in chloroform, and the encapsulation ability depended on the hydrophilicity of 3 and the molecular size of the dye. The rose bengal (RB) encapsulated polymer (RB/ 3 ) showed a slow release from the RB/ 3 system into water at neutral pH, while the release rate was significantly accelerated by the hydrolysis of the hydrophobic polymer shell under basic conditions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect