Assessing Patient-reported Quality of Life Outcomes in Vulva Cancer Patients: A Systematic Literature Review
| Autor: | Anne Lanceley, Ingvild Vistad, Pernille Tine Jensen, Vesna Bjelic Radisic, Tine H. Schnack, Karin Kuljanic, Anne Oberguggenberger, Claudia Schmalz, Ligita Paskeviciute Froeding, Razvan Galalaei, Andy Nordin, Elfriede Greimel |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Quality of life
medicine.medical_specialty MEDLINE Prom Disease law.invention 03 medical and health sciences Vulvar Neoplasms/psychology 0302 clinical medicine Randomized controlled trial law medicine Humans Patient Reported Outcome Measures 030219 obstetrics & reproductive medicine Vulvar Neoplasms business.industry Questionnaire BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Ginekologija i opstetricija Late effects BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Gynecology and Obstetrics Obstetrics and Gynecology medicine.disease female genital diseases and pregnancy complications vulva cancer quality of life questionnaire late effects Clinical trial Vulva cancer Lymphedema Systematic review Oncology 030220 oncology & carcinogenesis Physical therapy Quality of Life Female business |
| Zdroj: | European Organization of Research Treatment of Cancer Quality of Life Group the Gynecological Cancer group 2018, ' Assessing Patient-reported Quality of Life Outcomes in Vulva Cancer Patients : A Systematic Literature Review ', International Journal of Gynecological Cancer, vol. 28, no. 4, pp. 808-817 . https://doi.org/10.1097/IGC.0000000000001211 Froeding, L P, Greimel, E, Lancely, A, Oberguggenberger, A, Schmalz, C, Radisic, V, Nordin, A, Galalaei, R, Kuljanic, K, Vistad, I, Schnack, T & Jensen, P T 2018, ' Assessing patient reported quality of life outcomes in vulva cancer patients : a systematic literature review ', International Journal of Gynecological Cancer, vol. 28, no. 4, pp. 808–817 . https://doi.org/10.1097/IGC.0000000000001211 International Journal of Gynecologic Cancer Volume 28 Issue 4 |
| ISSN: | 1048-891X |
| DOI: | 10.1097/IGC.0000000000001211 |
| Popis: | ObjectivesVulva cancer (VC) treatment carries a high risk of severe late effects that may have a negative impact on quality of life (QoL). Patient-reported outcome measures (PROMs) are increasingly used when evaluating disease- and treatment-specific effects. However, the adequacy of measures used to assess sequelae and QoL in VC remains unclear. The aims of the present study were to evaluate disease- and treatment-related effects as measured by PROMs in VC patients and to identify available VC-specific PROMs.Methods/MaterialsA systematic literature search from 1990 to 2016 was performed. The inclusion criterion was report of disease- and treatment-related effects in VC patients using PROMs in the assessment. Methodological and reporting quality was in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. This systematic review was performed as part of phase 1 of the development of a European Organisation for Research and Treatment of Cancer QoL questionnaire for VC patients.ResultsThe search revealed 2299 relevant hits, with 11 articles extracted including a total of 535 women with VC; no randomized controlled trials were identified. The selected studies exhibited great heterogeneity in terms of PROMs use. Twenty-one different instruments assessed QoL. Most of the questionnaires were generic. Different issues (sexuality, lymphedema, body image, urinary and bowel function, vulva-specific symptoms) were reported as potentially important, but the results were not systematically collected. Only one VC-specific questionnaire was identified but did not allow for assessment and reporting on a scale level.ConclusionsVulva cancer treatment is associated with considerable morbidity deteriorating QoL. To date, there is no validated PROM available that provides adequate coverage of VC-related issues. The study confirms the need for a VC-specific QoL instrument with sensitive scales that allows for broad cross-cultural application for use in clinical trials. |
| Databáze: | OpenAIRE |
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