EFFECT OF HYPOPHYSECTOMY ON THE GROWTH HORMONE RESPONSE TO INSULIN-INDUCED HYPOGLYCAEMIA
| Autor: | H. J. Stewart, M. M. Roberts, A. P. M. Forrest, Suzanne H Richards, A. R. Boyns |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Blood Glucose
Radioisotopes medicine.medical_specialty Hypophysectomy business.industry Endocrinology Diabetes and Metabolism medicine.medical_treatment Breast Neoplasms Growth hormone Hypoglycemia Endocrinology Growth Hormone Pituitary Gland Internal medicine Yttrium Isotopes medicine Humans Insulin Female Insulin induced hypoglycaemia business |
| Zdroj: | Journal of Endocrinology. 58:637-641 |
| ISSN: | 1479-6805 0022-0795 |
| DOI: | 10.1677/joe.0.0580637 |
| Popis: | SUMMARY Plasma growth hormone (GH) levels were measured in 55 patients with advanced breast cancer, before and 3 months after pituitary ablation either by yttrium-90 implantation or by transethmoidal hypophysectomy. It was found that four of the 46 patients tested before ablation had an 'absent' GH response to insulin-induced hypoglycaemia. A comparison of the GH response to insulin-induced hypoglycaemia after yttrium implantation and transethmoidal hypophysectomy revealed no difference between the two procedures in the degree of pituitary ablation achieved. A partial GH deficiency occurred in 30% of patients after yttrium implantation but in only 4% after transethmoidal hypophysectomy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|