| Autor: |
Abdulla Alawadhi, Juan Pablo Appendino, Walter Hader, Bernard Rosenblatt, Jeremy T. Moreau, Francois Dubeau, Roy W.R. Dudley, Kenneth A. Myers |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of child neurology. 37(12-14) |
| ISSN: |
1708-8283 |
| Popis: |
Background Continuous spike wave in sleep (CSWS) is an electroencephalogram (EEG) pattern associated with developmental and epileptic encephalopathy with spike-and-wave activation in sleep (DEE-SWAS). This etiologically heterogeneous syndrome may occur because of genetic factors and congenital or acquired brain lesions. We studied the pattern of clinical presentation and underlying etiologies in patients with DEE-SWAS that respond to resective surgery. Methods We reviewed our clinical and research databases for patients who had resolution of CSWS following surgical resection of a focal lesion. Results We identified 5 patients meeting inclusion criteria. In 3 of 5, an epileptogenic structural abnormality was not apparent on brain magnetic resonance imaging (MRI). In all 3 patients, focal cortical dysplasia was identified through intracranial EEG monitoring. Significance DEE-SWAS may be a secondary bilateral network epilepsy syndrome, which can be treated with resection of the inciting focal lesion. In patients with drug-resistant CSWS, clinicians should consider a complete epilepsy presurgical workup, including intracranial EEG monitoring. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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