Hypercalcemia in distal renal tubular acidosis: A case report
| Autor: | Masoumeh Mohkam, Samaneh Parviz, Hedyeh Saneifard, Mahnaz Jamee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
endocrine system diseases Endocrinology Diabetes and Metabolism Anion gap 030209 endocrinology & metabolism Endocrinopathy urologic and male genital diseases Gastroenterology lcsh:Diseases of the endocrine glands. Clinical endocrinology Renal tubular acidosis 03 medical and health sciences 0302 clinical medicine Endocrinology Distal renal tubular acidosis Polyuria Internal medicine medicine Hypercalciuria 030212 general & internal medicine lcsh:RC648-665 business.industry nutritional and metabolic diseases Metabolic acidosis medicine.disease Hypokalemia Nephrocalcinosis Hypercalcemia medicine.symptom business |
| Zdroj: | Journal of Clinical and Translational Endocrinology Case Reports, Vol 18, Iss, Pp 100069-(2020) |
| ISSN: | 2214-6245 |
| Popis: | Introduction Hypercalcemia, defined as the total serum calcium concentration two standard deviations above the mean normal level, may be an emergency condition requiring proper initial diagnosis and immediate management. In association with nephrocalcinosis and hypercalciuria, differential diagnosis will be narrowed to limited diseases such as idiopathic hypercalciuria, hypervitaminosis A and D, and also renal tubular acidosis (RTA). Hypercalcemia is rarely presented in RTA with a few cases reported to date in the literature. Case presentation We reported a seven-month-old boy with complaints of refractory vomiting, restlessness, polyuria, polydipsia, and hypotonia. Laboratory tests revealed persistent hypercalcemia, hypokalemia, hypercalciuria, and metabolic acidosis with a normal anion gap. Bilateral nephrocalcinosis was detected in imaging studies. Based on these findings he was diagnosed with distal RTA and hypercalcemia and treated with polycitrate and Jaulie's solution. Conclusion Distal RTA should be considered as a differential diagnosis of hypercalcemia. Still, more studies are required for determining the pathway resulting in this rare association. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|