The effects of anaesthesia on experimental endotoxin shock

Autor:	N. A. Rety, C. M. Couves
Rok vydání:	1967
Předmět:	Under anaesthesia Experimental model business.industry Urination Blood Pressure General Medicine Hydrogen-Ion Concentration Shock Septic Endotoxin shock Endotoxins Dogs Anesthesiology and Pain Medicine Anesthesia Circulatory system Animals Humans Medicine Blood Gas Analysis Pulse business
Zdroj:	Canadian Anaesthetists’ Society Journal. 14:112-118
ISSN:	1496-8975 0008-2856
DOI:	10.1007/bf03003631
Popis:	Twenty-three healthy adult dogs were subjected to endotoxin shock to evaluate the effect of anaesthesia on circulatory parameters. Fifteen dogs were anaesthetized, while the remainder were exposed to endotoxin in the awake state. The results obtained indicate that the unanaesthetized animal is able to compensate during the process of circulatory deterioration following endotoxin and is a more rugged, but less reliable, experimental model. Experiments under anaesthesia are easier to perform and yield data which are not biased by the dog’s reaction to its environment. The anaesthetized animal is thus more ideally suited for this study.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749910ddda681c2cc8d66fb80f4c9556 https://doi.org/10.1007/bf03003631 Zobrazit plný text záznamu Full text from SpringerLink