Perspective: The Dietary Inflammatory Index (DII)—Lessons Learned, Improvements Made, and Future Directions
| Autor: | Thomas G. Hurley, James R. Hébert, James R. Hussey, Nitin Shivappa, Michael D. Wirth |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Gerontology 030109 nutrition & dietetics Nutrition and Dietetics Dietary assessment Human studies business.industry Clinical study design Perspective (graphical) Medicine (miscellaneous) 030209 endocrinology & metabolism Nutrient intake Health outcomes 03 medical and health sciences 0302 clinical medicine Perspective Medicine Observational study Total energy business Food Science |
| Zdroj: | Advances in Nutrition. 10:185-195 |
| ISSN: | 2161-8313 |
| DOI: | 10.1093/advances/nmy071 |
| Popis: | The literature on the role of inflammation in health has grown exponentially over the past several decades. Paralleling this growth has been an equally intense focus on the role of diet in modulating inflammation, with a doubling in the size of the literature approximately every 4 y. The Dietary Inflammatory Index (DII) was developed to provide a quantitative means for assessing the role of diet in relation to health outcomes ranging from blood concentrations of inflammatory cytokines to chronic diseases. Based on literature from a variety of different study designs ranging from cell culture to observational and experimental studies in humans, the DII was designed to be universally applicable across all human studies with adequate dietary assessment. Over the past 4 y, the DII has been used in >200 studies and forms the basis for 12 meta-analyses. In the process of conducting this work, lessons were learned with regard to methodologic issues related to total energy and nutrient intake and energy and nutrient densities. Accordingly, refinements to the original algorithm have been made. In this article we discuss these improvements and observations that we made with regard to misuse and misinterpretation of the DII and provide suggestions for future developments. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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