Transcranial Magnetic Stimulation and Working Memory Training to Address Language Impairments in Aphasia : A Case Study
| Autor: | Maria Kambanaros, Despina Kranou-Economidou |
|---|---|
| Přispěvatelé: | Kranou-Economidou, Despina, Kambanaros, Maria |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Working memory training
Male medicine.medical_specialty Article Subject medicine.medical_treatment Neurosciences. Biological psychiatry. Neuropsychiatry Audiology Medical and Health Sciences short term memory Dorsolateral Prefrontal Cortex Aphasia Health Sciences medicine Humans Learning aphasis Language Development Disorders Rehabilitation Working memory General Medicine Middle Aged medicine.disease Transcranial Magnetic Stimulation Transcranial magnetic stimulation Neuropsychology and Physiological Psychology Multiple baseline design Memory Short-Term Neurology Brain stimulation Quality of Life Receptive aphasia transcranial magnetic stimulation TMS Neurology (clinical) medicine.symptom Psychology language impairments RC321-571 Research Article |
| Zdroj: | Behavioural Neurology Behavioural Neurology, Vol 2021 (2021) |
| Popis: | Background: traditionally, people with aphasia (PWA) are treated with impairment-based language therapy to improve receptive and expressive language skills. In addition to language deficits, PWA are often affected by some level of working memory (WM) impairments. Both language and working memory impairments combined have a negative impact on PWA’s quality of life. The aim of this study was to investigate whether the application of intermittent theta-burst stimulation (iTBS) combined with computerized WM training will result in near-ransfer effects (i.e., trained WM) and far-transfer effects (i.e., untrained language tasks) and have a positive effect on the quality of life of PWA. Methods: the participant was a 63-year-old Greek-Cypriot male who presented with mild receptive aphasia and short-term memory difficulties. Treatment was carried out using a multiple baseline (MB) design composed of a pretherapy or baseline testing phase, a therapy phase, and a posttherapy/follow-up phase. The treatment program involved iTBS application to the left dorsolateral prefrontal cortex (DLPFC), an area responsible for WM, for 10 consecutive sessions. The participant received a 3-minute iTBS application followed by 30-minute computer-assisted WM training. Outcome measures included a WM screening test, a standardized aphasia test, a nonverbal intelligence test, story-telling speech samples, a procedural discourse task, and a questionnaire addressing quality of life. These measures were performed three times before the treatment, immediately upon completion of the treatment, and once during follow-up testing at 3 months posttreatment. Results: we found a beneficial effect of iTBS and WM training on naming, reading, WM, reasoning, narrative, communication efficiency, and quality of life (QoL). Implications for Rehabilitation: noninvasive brain stimulation combined with computerized WM training may be used in aphasia rehabilitation to improve WM and generalize to language improvement. Refereed/Peer-reviewed |
| Databáze: | OpenAIRE |
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