Performance of polymethyl pentene oxygenators for neonatal extracorporeal membrane oxygenation: a comparison with silicone membrane oxygenators
| Autor: | Giles J. Peek, Suneel Pooboni, Espeed Khoshbin, Andrzej W. Sosnowski, David Machin, Hilliary M. Killer, Claire Westrope, Richard K. Firmin |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Coagulation protein medicine.medical_specialty Oxygenators medicine.medical_treatment Silicones Polyenes 030204 cardiovascular system & hematology 03 medical and health sciences chemistry.chemical_compound Extracorporeal Membrane Oxygenation 0302 clinical medicine Silicone medicine Extracorporeal membrane oxygenation Humans Radiology Nuclear Medicine and imaging Oxygenator Oxygenators Membrane Retrospective Studies Advanced and Specialized Nursing business.industry Hemodynamics Infant Newborn Thrombosis Equipment Design General Medicine Oxygenation Respiration Disorders Survival Analysis Silicone membrane Surgery 030228 respiratory system chemistry Pentene Equipment Failure Female Cardiology and Cardiovascular Medicine business Safety Research Biomedical engineering |
| Zdroj: | Perfusion. 20:129-134 |
| ISSN: | 1477-111X 0267-6591 |
| DOI: | 10.1191/0267659105pf797oa |
| Popis: | Objective: To review the performance of polymethyl pentene versus silicone oxygenators in terms of efficiency in priming and oxygenation, oxygenator resistance, requirements for coagulation proteins and consumption of blood products, for neonatal extracorporeal membrane oxygenation (ECMO) patients. Study design: Forty consecutive neonates were selected retrospectively pre- and post-introduction of the new polymethyl pentene (PMP) oxygenators. They formed two equal groups. After calculation of the sample size, data were collected from ELSO registry forms and patient records. Results were analysed using parametric and non-parametric tests. Results: Neonatal PMP (N-PMP) oxygenators were smaller, faster and easier to prime. They were less efficient than silicone oxygenators, especially in carbon dioxide elimination, and, therefore, required higher sweeps. The preservation of coagulation proteins was significantly better, but there was no reduction in the consumption of blood products, despite having less than half the surface area and significantly lower blood path resistance. Conclusion: Small PMP oxygenators (Medos Hilite 800 LT) provide adequate gas exchange and offer technical advantages in terms of more efficient priming, reduced haemodynamic resistance and better control and preservation of coagulation proteins than silicone oxygenators. |
| Databáze: | OpenAIRE |
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