Mental fatigue-induced decrease in levels of several plasma amino acids
| Autor: | T. Shirai, Hiroshi Mizuma, Y. Kajimoto, Masaaki Tanaka, Y. Kataoka, Osami Kajimoto, T. Sugino, K. Yamaguti, Satoshi Nozaki, Yasuyoshi Watanabe, Tetsuya Sasabe, Hirohiko Kuratsune, Kei Mizuno |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Blood Glucose Male Relaxation medicine.medical_specialty Time Factors Arginine Lysine Trail Making Test Down-Regulation Neuropsychological Tests chemistry.chemical_compound Internal medicine medicine Humans Amino Acids Tyrosine Serum Albumin Biological Psychiatry Brain Chemistry chemistry.chemical_classification Methionine Albumin Brain Mental Fatigue Amino acid Psychiatry and Mental health Cholesterol Endocrinology Neurology chemistry Biochemistry Female Neurology (clinical) Amino Acids Branched-Chain Cysteine |
| Zdroj: | Journal of Neural Transmission. 114:555-561 |
| ISSN: | 1435-1463 0300-9564 |
| DOI: | 10.1007/s00702-006-0608-1 |
| Popis: | To investigate the relation between plasma amino acid levels and mental fatigue, we measured the plasma concentrations of 20 amino acids in 9 healthy volunteers before and after a fatigue-inducing mental task session for 8 hr. As fatigue-inducing mental tasks, the subjects performed an advanced trail making test, a Japanese KANA pick up test, and a mirror drawing test. As a control, 8-hr relaxation session was performed in the same subjects at an interval of 4 weeks. Immediately after the fatigue session, the plasma levels of branched-chain amino acids, tyrosine, cysteine, methionine, lysine, and arginine were below those after a relaxation session. The values for other blood parameters including total protein, albumin, glucose, and total cholesterol did not show any differences between the 2 sessions. These results indicate that mental fatigue may be characterized by a decrease in the plasma level of these amino acids. |
| Databáze: | OpenAIRE |
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