Metiamide treatment in five patients with Zollinger-Ellison syndrome
| Autor: | Bernades P, Michel Mignon, G. Kloeti, R. Lambert, Accary Jp, J.J. Bernier, Serge Bonfils, C. L’Hirondel |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors education Metiamide Gastroenterology Zollinger-Ellison Syndrome Internal medicine Gastrins medicine Humans Gastrin Gastric Juice Dose-Response Relationship Drug business.industry Thiourea Middle Aged medicine.disease Zollinger-Ellison syndrome Female business Secretory Rate medicine.drug |
| Zdroj: | Digestion. 15(1) |
| ISSN: | 0012-2823 |
| Popis: | Five patients with Zollinger-Ellison syndrome received metiamide per os in doses ranging from 600 to 1,200 mg/day for a minimum period of 2 weeks. Drug produced an inhibition of basal gastric acid secretion ranging from 5 to 100% with relief of symptoms. Survey of patients during and after metiamide course showed sometimes a prolonged antisecretory effect up to 26 days after the end of treatment or, on the contrary, a reduced drug activity in spite of increasing doses. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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