Biological properties of a highly purified preparation of 17-alpha estradiol
| Autor: | Preston L. Perlman, Gordon B. Thomas, James W. Cassidy |
|---|---|
| Rok vydání: | 1955 |
| Předmět: |
medicine.medical_specialty
Anabolism Estradiol Chemistry Alpha (ethology) Estrogens General Biochemistry Genetics and Molecular Biology Endocrinology Estradiol Congeners Internal medicine Biological property Pituitary gonadotrophin medicine Contraceptive Agents Female Humans Female hormones hormone substitutes and hormone antagonists |
| Zdroj: | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 88(1) |
| ISSN: | 0037-9727 |
| Popis: | Summary1 The anabolic. The estrogenic and the pituitary gonadotrophin inhibiting actions table of a highly purified sample of α-estradiol have been studied in experimental animals. 2. It appears that α-estradiol has not significant anabolic action and that the weak estrogenic and gonadotrophin inhibiting activities might be due to contamination with a very small amount of the potent β-epimer. 3. If the activity found in this preparation is truly due to α-estradiol has one-two hundred fiftieth the gonadotrophin inhibiting activity of β-estradiol and approximately one-three hundred fiftieth the estrogenic activigy. |
| Databáze: | OpenAIRE |
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