Oral antimicrobial susceptibilities of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis isolates from Japanese children
| Autor: | Akira Kamenosono, Masao Yoshinaga, Kunihiro Manago, Kaori Masuda, Junichiro Nishi, Koichi Tokuda, Koichiro Miyata, Ryuji Masuda |
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| Rok vydání: | 2002 |
| Předmět: |
Microbiology (medical)
Haemophilus Infections medicine.drug_class Antibiotics Administration Oral Microbial Sensitivity Tests Biology medicine.disease_cause Pneumococcal Infections Haemophilus influenzae Microbiology Moraxella catarrhalis Minimum inhibitory concentration Japan Streptococcus pneumoniae medicine Humans Pharmacology (medical) Child Respiratory Tract Infections Antibacterial agent General Medicine Antimicrobial biology.organism_classification Virology Anti-Bacterial Agents Infectious Diseases Gram-Negative Bacterial Infections Cefditoren medicine.drug |
| Zdroj: | International Journal of Antimicrobial Agents. 20:130-135 |
| ISSN: | 0924-8579 |
| Popis: | The minimum inhibitory concentrations (MICs) of 11 oral antibiotics were measured for 140 Streptococcus pneumoniae, 115 Haemophilus influenzae, and 46 Moraxella catarrhalis strains isolated from Japanese children. The antibiotics selected included a range of commonly prescribed agents together with a selection of new cefems and a penem. Cefditoren was most active against the highly penicillin resistant S. pneumoniae, beta-lactamase-producing H. influenzae and beta-lactamase-negative ampicillin-resistant H. influenzae. However, amoxycillin retained good activity against the penicillin-susceptible or -intermediately resistant S. pneumoniae (88.6%) and most of ampicillin-susceptible or -intermediately resistant H. influenzae (87.9%). We thus consider that amoxycillin remains a useful initial choice for the treatment of paediatric respiratory infections in Japan. |
| Databáze: | OpenAIRE |
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