ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS
Autor: | Everardo Albuquerque Menezes, Auberson Martins Maciel, Bruno N.M.F. Castro, Francisco Afrânio Cunha, E. J. J. Mallmann, Pierre Basílio Almeida Fechine |
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Rok vydání: | 2015 |
Předmět: |
lcsh:Arctic medicine. Tropical medicine
Antifungal Agents Silver lcsh:RC955-962 Reducing agent Metal Nanoparticles Nanoparticle Microbial Sensitivity Tests Silver nanoparticle Metal chemistry.chemical_compound Candida albicans Humans Antifungal activity Candida tropicalis Sodium dodecyl sulfate Candida spp biology General Medicine biology.organism_classification Antimicrobial Corpus albicans Infectious Diseases chemistry visual_art visual_art.visual_art_medium Silver nanoparticles Brief Communications Bacteria Nuclear chemistry |
Zdroj: | Revista do Instituto de Medicina Tropical de São Paulo Revista do Instituto de Medicina Tropical de São Paulo, Vol 57, Iss 2, Pp 165-167 (2015) Revista do Instituto de Medicina Tropical de São Paulo, Volume: 57, Issue: 2, Pages: 165-167, Published: APR 2015 |
ISSN: | 0036-4665 |
DOI: | 10.1590/s0036-46652015000200011 |
Popis: | Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment. Nanopartículas de Prata (AgNPs) são estruturas metálicas em escala nanométrica. AgNPs apresentam atividades antimicrobianas contra fungos e bactérias; no entanto, a síntese de AgNPs pode gerar resíduos tóxicos e devido a isso novas rotas utilizando compostos atóxicos têm sido buscadas. O objetivo desse estudo foi sintetizar AgNPs utilizando a ribose como agente redutor e dodecil sulfato de sódio (SDS) como estabilizante e avaliar a atividade antifúngica dessas partículas contra C. albicans e C. tropicalis. Foram sintetizadas nanopartículas estáveis com 12,5 ± 0,2 nm (média ± DP) que apresentaram elevada atividade contra Candida spp. e podem representar boa alternativa no tratamento de infecções fúngicas. |
Databáze: | OpenAIRE |
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