Ibuprofen Arginate for Rapid-Onset Pain Relief in Daily Practice: A Review of Its Use in Different Pain Conditions
| Autor: | Juan Pérez Cajaraville |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Drug
Ibuprofen arginate analgesic efficacy media_common.quotation_subject Pain relief arginine Review 03 medical and health sciences 0302 clinical medicine Pharmacokinetics 030202 anesthesiology Oral administration Daily practice Medicine media_common business.industry organic chemicals ibuprofen arginate Ibuprofen Anesthesiology and Pain Medicine Tolerability Anesthesia business pharmacokinetics 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Journal of Pain Research |
| ISSN: | 1178-7090 |
| DOI: | 10.2147/jpr.s280571 |
| Popis: | Ibuprofen is one of the most frequently used analgesics. One of the concerns related with the oral administration of conventional ibuprofen is the relatively slow absorption, which is clinically a relative inconvenience when rapid-onset analgesic effect is required in patients suffering from acute moderate/severe pain. A new oral dosage formulation of ibuprofen containing the L-arginine salt of ibuprofen (ibuprofen arginate) has been commercialized for more than two decades, but data reported in the literature are relatively scarce. This article presents salient findings on pharmacokinetics, pharmacological activity, clinical efficacy and tolerability of ibuprofen arginate, with the purpose to provide clinicians with a summary overview of some frequent acute pain conditions, such as dental pain, dysmenorrhea, headache or postoperative pain in which ibuprofen arginate may be considered the drug of choice in individual patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|