Clinical Versus Pathologic Laryngeal Cancer Staging and the Impact of Stage Change on Outcomes
| Autor: | David I. Zimmer, Bryan Hair, Patrick Tassone, Brandon Prendes, Kevin J. Contrera, Chandana A. Reddy, Brian B. Burkey |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Laryngectomy Gastroenterology 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Odds Ratio Humans Stage (cooking) 030223 otorhinolaryngology Laryngeal Neoplasms Cancer staging Aged Neoplasm Staging Proportional Hazards Models Retrospective Studies Salvage Therapy Proportional hazards model business.industry Hazard ratio Margins of Excision Retrospective cohort study Odds ratio Perioperative Middle Aged Logistic Models Treatment Outcome Otorhinolaryngology 030220 oncology & carcinogenesis Carcinoma Squamous Cell Female Neoplasm Recurrence Local business |
| Zdroj: | The LaryngoscopeBIBLIOGRAPHY. 131(3) |
| ISSN: | 1531-4995 |
| Popis: | OBJECTIVES/HYPOTHESIS Evaluate the impact and accuracy of clinical laryngeal cancer staging. STUDY DESIGN Retrospective cohort study. METHODS Two hundred sixty-five consecutive patients with laryngeal squamous cell carcinoma who underwent total laryngectomy from 2001 to 2017 were studied. Clinical versus pathologic tumor (T) and nodal (N) categories were compared. Logistic regression and Cox proportional hazards analyzed the association of stage change with perioperative factors and outcomes. RESULTS Forty-seven patients (17.7%, accuracy = 0.969 ± 0.010 [standard error]) changed between T1-2 and T3-4. Sixty-four patients (24.1%, accuracy = 0.866 ± 0.020) had inaccurate N category. Salvage patients were less likely to have stage change (downstage: odds ratio [OR] = 0.20, 95% confidence interval [CI]: 0.08-0.50, P |
| Databáze: | OpenAIRE |
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