The role of carotid stenosis ultrasound scale in the prediction of ischemic stroke

Autor:	Jianyu Zhang, Yongjin Zhang, Zeng-Lin Cai, Pin Meng, Xiaobing He, Taotao Wu, Yi Tang, Bei Wang, Xinyu Zhou, Yingda Xu, Xiaoqin Niu, Bo Zhang, Mingli He, Yong’an Sun, Mingyu Wang, Bingchao Xu, Zaipo Li, Ying Shi, Niu Ji, Ru Yang, Bei Xu, Guanghui Zhang
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Male medicine.medical_specialty Neurology genetic structures Neuroimaging Dermatology Sensitivity and Specificity 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Internal medicine Ultrasound medicine Brain ischemic Carotid stenosis Humans Prospective Studies Prospective cohort study Vertebral Artery Neuroradiology Aged Ischemic Stroke Receiver operating characteristic business.industry Ultrasonography Doppler General Medicine Blood flow Cerebral blood flow Middle Aged medicine.disease bacterial infections and mycoses Psychiatry and Mental health Stenosis Cardiology Original Article Female Neurology (clinical) business 030217 neurology & neurosurgery Carotid Artery Internal
Zdroj:	Neurological Sciences
ISSN:	1590-3478 1590-1874
Popis:	Introduction To improve the accuracy of ultrasound techniques for the assessment of carotid stenosis, we designed a novel carotid artery stenosis ultrasound scale (CASUS), and evaluated its accuracy, reliability, and its value in predicting the occurrence of cardiovascular and cerebrovascular diseases in a prospective study. Methods A total of 750 patients with first-time ischemic stroke and hospitalized within 24 h were enrolled in the study. Using color Doppler ultrasound (CDUS), the degree of stenosis and blood flow (BF) in bilateral internal carotid arteries (ICA) and the V1-V3 segment of vertebral arteries (VA) was assessed. Cubic simulation curves for BF and global blood flow (GBF) over the stenosis score (SS), total stenosis score (TSS), and radiological imaging- total stenosis score (RI-TSS) were fitted and compared. The receiver operating characteristic (ROC) curves using TSS, RI-TSS, or GBF to predict various ischemic stroke endpoints were also analyzed and compared. Results There was a linear relationship between SS and BF both ICA and VA (R2 were 0.734 and 0.783, respectively, both P P P P > 0.05). Conclusions The novel CASUS can better reflect the level of cerebral reperfusion in patients with ischemic stroke and can better predict the occurrence of cardiovascular and cerebrovascular diseases.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7466ffd93d1081991935965f1c0010dd http://europepmc.org/articles/PMC7196942 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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