Nitroepoxide ring opening with thionucleophiles in water: synthesis of α-xanthyl ketones, β-keto sulfones and β-keto sulfonic acids

Autor:	Hossein Rahimzadeh, Azizollah Habibi, Azim Ziyaei Halimehjani, Ali Sharifi, Elham Badali
Rok vydání:	2020
Předmět:	chemistry.chemical_compound chemistry Sodium bisulfite Sodium Aryl Potassium Organic Chemistry chemistry.chemical_element Physical and Theoretical Chemistry Ring (chemistry) Biochemistry Medicinal chemistry
Zdroj:	Organic & Biomolecular Chemistry. 18:4983-4987
ISSN:	1477-0539 1477-0520
DOI:	10.1039/d0ob00941e
Popis:	Nitroepoxide ring opening with thionucleophiles such as potassium xanthates, sodium aryl sulfinates and sodium bisulfite in water is investigated. It provides a direct and green route for the synthesis of α-xanthyl-α-aryl-2-propanones (P2P-xanthate derivatives), β-keto sulfones and β-keto sulfonic acids. High to excellent yields, performing the reaction in water under catalyst-free conditions, and easy work-up are the main advantages of this protocol.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7461d993e2dff81dcb24ebf1f5d42d18 https://doi.org/10.1039/d0ob00941e Zobrazit plný text záznamu