BreakthroughSaprochaete capitatainfections in patients receiving echinocandins: case report and review of the literature

Autor: Axel Jeurissen, Jan Verhaegen, Katrien Lagrou, M. van Bergen, Ignace Surmont, Lieve Coorevits, C. Schuermans
Rok vydání: 2011
Předmět:
Zdroj: Medical Mycology. 49:414-418
ISSN: 1460-2709
1369-3786
DOI: 10.3109/13693786.2010.535179
Popis: We report a rare case of a fatal Saprochaete capitata breakthrough infection in a patient with acute myeloid leukemia receiving empirical caspofungin therapy. S. capitata is an uncommon, yet emerging cause of invasive infections, especially in patients with haematological malignancies. Blood cultures from our patient yielded S. capitata which was found to be resistant, in vitro, to caspofungin. We consecutively reviewed all published cases of breakthrough infections caused by S. capitata in patients receiving echinocandins. S. capitata should be considered in those patients who remain febrile or who develop invasive mould infections while under echinocandin therapy.
Databáze: OpenAIRE