Delineation of the functional properties and the mechanism of action of AA29504, an allosteric agonist and positive allosteric modulator of GABA
| Autor: | Emma Rie Olander, Nawid Madjroh, Lennart Bunch, Pella Cecilia Söderhielm, Anders A. Jensen |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Pharmacology 030102 biochemistry & molecular biology Dose-Response Relationship Drug Receptors GABA-A Biochemistry 03 medical and health sciences Xenopus laevis 0302 clinical medicine Allosteric Regulation Animals Humans GABA-A Receptor Agonists GABA Modulators 030217 neurology & neurosurgery Allosteric Site |
| Zdroj: | Biochemical pharmacology. 150 |
| ISSN: | 1873-2968 |
| Popis: | The retigabine analog 2-amino-4-[(2,4,6-trimethylbenzylamino)-phenyl]-carbamic acid ethyl ester (AA29504) is a positive allosteric modulator (PAM) of γ-aminobutyric acid |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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