Vascular Response Occurring at 3 Months After Everolimus-Eluting Cobalt–Chromium Stent Implantation in Patients With ST-Segment Elevation Myocardial Infarction vs. Stable Coronary Artery Disease
| Autor: | Toshiro Shinke, Junya Shite, Tomonori Itoh, Tatsuo Kikuchi, Masaru Ishida, Takahide Suzuki, Kiyoshi Hibi, Takahiro Sawada, Takayuki Okamura, Fumiaki Takahashi, Hiromasa Otake, Takatoshi Hayashi, Daisuke Terashita, Yoshiaki Ito, Yoshihiro Morino, Takashi Morita, Yoshiro Tsukiyama |
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| Rok vydání: | 2020 |
| Předmět: |
Chromium
medicine.medical_specialty medicine.medical_treatment Lumen (anatomy) Coronary Artery Disease 030204 cardiovascular system & hematology Coronary artery disease 03 medical and health sciences Percutaneous Coronary Intervention 0302 clinical medicine Internal medicine medicine Humans ST segment In patient Everolimus Prospective Studies cardiovascular diseases 030212 general & internal medicine Myocardial infarction Thrombus business.industry Stent Drug-Eluting Stents Thrombosis Cobalt General Medicine medicine.disease Treatment Outcome surgical procedures operative Cardiology ST Elevation Myocardial Infarction Cardiology and Cardiovascular Medicine business Tomography Optical Coherence medicine.drug |
| Zdroj: | Circulation Journal. 84:1941-1948 |
| ISSN: | 1347-4820 1346-9843 |
| DOI: | 10.1253/circj.cj-20-0264 |
| Popis: | BACKGROUND Second-generation drug-eluting stents (DES) reduce the incidence of stent thrombosis, even in patients with ST-segment elevated myocardial infarction (STEMI). However, the early local vascular healing after DES implantation in STEMI lesions, which mainly concerns stent thrombosis, is still unclear.Methods and Results:We attempted to determine early local vascular healing 3 months after cobalt-chromium everolimus-eluting stent (CoCr-EES) implantation in STEMI lesions relative to stable coronary artery disease (CAD) lesions. This prospective, multicenter study analyzed 96 total lesions (STEMI=49, stable CAD=51) by frequency domain-optical coherence tomography (FD-OCT) performed post-procedure and at the 3-month follow-up. Although CoCr-EES implanted in STEMI were almost entirely covered at 3 months, they had a relatively high incidence of uncovered struts compared with stable CAD (5.5% vs. 1.6%, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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