Evolution of the Dynein Heavy Chain Family in Ciliates
| Autor: | David E. Wilkes, Vidyalakshmi Rajagopalan |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Most recent common ancestor Genetics Ciliate Oxytricha Paramecium biology Dynein Tetrahymena Dyneins macromolecular substances biology.organism_classification Microbiology Evolution Molecular Motor protein 03 medical and health sciences 030104 developmental biology Gene family Amino Acid Sequence Ciliophora Phylogeny |
| Zdroj: | Journal of Eukaryotic Microbiology. 63:138-141 |
| ISSN: | 1550-7408 1066-5234 |
| DOI: | 10.1111/jeu.12245 |
| Popis: | Dynein heavy chains are motor proteins that comprise a large gene family found across eukaryotes. We have investigated this gene family in four ciliate species: Ichthyophthirius, Oxytricha, Paramecium, and Tetrahymena. Ciliates appear to encode more dynein heavy chain genes than most eukaryotes. Phylogenetic comparisons demonstrated that the last common ancestor of the ciliates that were examined expressed at least 14 types of dynein heavy chains with most of the expansion coming from the single-headed inner arm dyneins. Each of the dyneins most likely performed different functions within the cell. |
| Databáze: | OpenAIRE |
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