Associations between preconception macronutrient intake and birth weight across strata of maternal BMI

Autor: Jan Jaap H. M. Erwich, Marian K. Bakker, Petra C Vinke, Nastaran Salavati, Farya Mubarik, Fraser I. Lewis, Eline M. van der Beek
Přispěvatelé: Reproductive Origins of Adult Health and Disease (ROAHD), Center for Liver, Digestive and Metabolic Diseases (CLDM)
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Physiology
Maternal Health
Glycobiology
GLYCEMIC-LOAD
Biochemistry
Body Mass Index
Cohort Studies
Mathematical and Statistical Techniques
Pregnancy
Medicine and Health Sciences
Birth Weight
Medicine
RISK
OUTCOMES
Multidisciplinary
Organic Compounds
Statistics
Obstetrics and Gynecology
Gestational age
Chemistry
Physiological Parameters
Research Design
CARDIOVASCULAR-DISEASE
Physical Sciences
Cohort
Regression Analysis
Female
NUTRITION
Research Article
Maternal Age
Cohort study
Adult
Offspring
Science
Birth weight
Carbohydrates
Nutritional Status
Linear Regression Analysis
Research and Analysis Methods
DIET
Polysaccharides
DUTCH FAMINE
Glycemic load
Humans
Statistical Methods
PRENATAL EXPOSURE
business.industry
Body Weight
Organic Chemistry
Chemical Compounds
Biology and Life Sciences
Maternal Nutritional Physiological Phenomena
Nutrients
medicine.disease
ENERGY-INTAKE
Food
Linear Models
Women's Health
business
Body mass index
EARLY-PREGNANCY
Mathematics
Demography
Zdroj: PLoS ONE, 15(12):0243200. PUBLIC LIBRARY SCIENCE
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0243200 (2020)
ISSN: 1932-6203
Popis: Introduction Maternal nutrition during pregnancy is linked with birth outcomes including fetal growth, birth weight, congenital anomalies and long-term health through intra-uterine programming. However, a woman’s nutritional status before pregnancy is a strong determinant in early embryo-placental development, and subsequently outcomes for both mother and child. Therefore, the aim of this study was to investigate the association between dietary macronutrient intake in the preconception period with birth weight. Methods We studied a group of 1698 women from the Dutch Perined-Lifelines linked birth cohort with reliable detailed information on preconception dietary macronutrient intake (using a semi quantitative food frequency questionnaire) and data available on birth weight of the offspring. Birth weight was converted into gestational age adjusted z-scores, and macronutrient intake was adjusted for total energy intake using the nutrient residual method. Preconception BMI was converted into cohort-based quintiles. Multivariable linear regression was performed, adjusted for other macronutrients and covariates. Results Mean maternal age was 29.5 years (SD 3.9), preconception BMI: 24.7 kg/m2 (SD 4.2) and median daily energy intake was 1812 kcal (IQR 1544–2140). Mean birth weight was 3578 grams (SD 472). When adjusted for covariates, a significant association (adjusted z score [95% CI], P) between polysaccharides and birth weight was shown (0.08 [0.01–0.15], 0.03). When linear regression analyses were performed within cohort-based quintiles of maternal BMI, positive significant associations between total protein, animal protein, fat, total carbohydrates, mono-disaccharides and polysaccharides with birth weight were shown in the lowest quintile of BMI independent of energy intake, intake of other macronutrients and covariates. Conclusion Out of all macronutrients studied, polysaccharides showed the strongest association with birth weight, independent of energy intake and other covariates. Our study might suggest that specifically in women with low preconception BMI a larger amount of macronutrient intake was associated with increased birth weight. We recommend that any dietary assessment and advise during preconception should be customized to preconception weight status of the women.
Databáze: OpenAIRE
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