Allergen variability and house dust mite sensitivity in pre-school children with allergic complaints
| Autor: | Melike Kurtuluş-Çokboz, Soner Güneş, Selçuk Yazıcı, Gülce Baranlı, Sezin Aşik-Akman, Demet Can, Özlem Kemer |
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| Přispěvatelé: | Tıp Fakültesi |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Hypersensitivity
Immediate Male medicine.medical_specialty Allergy Turkey Urticaria Allergen Sensitization medicine.disease_cause Alternaria alternata Dermatitis Atopic Allergic sensitization 03 medical and health sciences 0302 clinical medicine Allergen Food allergy 030225 pediatrics Prevalence Medicine Animals Humans Antigens Dermatophagoides Asthma Retrospective Studies Skin Tests House dust mite biology business.industry Pyroglyphidae Pre-School Children Atopic dermatitis Allergens medicine.disease biology.organism_classification Dermatology respiratory tract diseases Cross-Sectional Studies 030228 respiratory system Child Preschool Pediatrics Perinatology and Child Health Cats House Dust Mite Pollen Female business Food Hypersensitivity |
| Popis: | Yazici S, Gunes S, Kurtulus-Cokboz M, Kemer O, Baranli G, Asik-Akman S, Can D. Allergen variability and house dust mite sensitivity in pre-school children with allergic complaints. Turk J Pediatr 2018; 60: 41-49. The increase in the prevalence of allergic diseases in pre-school children who are often at home may be due to an increase in house dust mite sensitivity, which is rarely expected in this age group. In our study, it was aimed to investigate allergen sensitivities, especially house dust mite sensitivity in pre-school children with allergic disease complaints by skin prick test (SPT). Two hundred and twenty children admitted to the Pediatric Allergy and Asthma Clinic of Balikesir University between October 2015 and October 2016 diagnosed with asthma, allergic rhinitis, food allergy, atopic dermatitis or urticaria were involved in the retrospective cross-sectional study. Allergen groups used in SPT were Dermatophagoides farina (Derf), Dermatophagoides pteronyssinus (Der p), Alternaria alternata, cat epithelium, pollen mixture and food mixture. Average age of the 220 patients was 2.98 years (2.75-3.21). SPT was positive in 55.9% of patients. Sixteen percent were monosensitized and 73.8% were polysensitized. Seventy two children (32.7%) were sensitive to Der f and 67 (30.4%) were sensitive to Der p. There was no difference between SPT positivity and gender (p > 0.05). Ninty-five children were diagnosed with asthma, 38 with asthma and allergic rhinitis, 63 with food allergy and 24 with urticaria and/or atopic dermatitis. SPT positivity was significantly higher in the asthma and allergic rhinitis group than other groups. As the age increased, significant increases in the sensitivities of Der f (p < 0.01), Der p (P < 0.01) and A. alternata (p < 0.05) and a significant decrease for food panel sensitivity (p < 0.01) were detected. Even though skin and food allergies were included in our study, house dust mite sensitivity was found much higher than other studies reporting ranges between 3.5-23% in children of the same age group with mainly respiratory complaints. It is concluded that the probable reasons for this increase, especially geographical features, should be investigated in different areas and in larger number of studies. |
| Databáze: | OpenAIRE |
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