Genome chromatinization in giant double-stranded DNA viruses

Autor: Mart Krupovic, Ying Liu
Přispěvatelé: Virologie des archées - Archaeal Virology, Université Paris Cité (UPCité)-Microbiologie Intégrative et Moléculaire (UMR6047), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Trends in Biochemical Sciences
Trends in Biochemical Sciences, 2022, 47 (1), pp.3-5. ⟨10.1016/j.tibs.2021.10.002⟩
ISSN: 0968-0004
DOI: 10.1016/j.tibs.2021.10.002⟩
Popis: International audience; Giant viruses have extravagantly large double-stranded (ds)DNA genomes that are packaged into exceedingly complex virions. In two recent papers, Liu et al. and Valencia-Sánchez, Abini-Agbomson et al. show that some giant viruses encode unique histone doublets, which form nucleosomes remarkably similar to those found across the eukaryotic domain of life.
Databáze: OpenAIRE