Impact of varying anatomic sites on advanced stage and survival of oral cancer: 9-year prospective cohort of 27 717 cases

Autor: Yi Huah Lee, William Wang Yu Su, Shu Lin Chuang, Han-Mo Chiu, Tony Hsiu Hsi Chen, Chiu Wen Su, Sam Li Sheng Chen, Yi-Chia Lee, Jean Ching Yuan Fann, Amy Ming Fang Yen, Chen Yang Hsu, Cheng-Ping Wang, Sherry Yueh Hsia Chiu, Dun Cheng Chang, Ya Chung Jeng, Mu Kuan Chen
Rok vydání: 2018
Předmět:
Male
Palate
Hard
Gingiva
Oropharynx
Cohort Studies
0302 clinical medicine
Cause of Death
Odds Ratio
Prospective Studies
Prospective cohort study
Early Detection of Cancer
education.field_of_study
Hazard ratio
Smoking
Middle Aged
Alcoholism
medicine.anatomical_structure
030220 oncology & carcinogenesis
population characteristics
Female
Mouth Neoplasms
Adult
medicine.medical_specialty
Population
Taiwan
Risk Assessment
Disease-Free Survival
03 medical and health sciences
Young Adult
stomatognathic system
Tongue
Internal medicine
medicine
Confidence Intervals
Humans
Neoplasm Invasiveness
education
Mouth Floor
Aged
Neoplasm Staging
business.industry
Cancer
030206 dentistry
Odds ratio
medicine.disease
Survival Analysis
Confidence interval
stomatognathic diseases
Cheek
Otorhinolaryngology
Hard palate
business
Zdroj: Headneck. 41(5)
ISSN: 1097-0347
Popis: Background To elucidate the impact of varying anatomic sites on advanced stage of and death from oral cancer. Methods A total of 27 717 oral cancers mainly from a population-based visual inspection program in Taiwan from 2004 to 2009 was followed until the end of 2012. Results Using lip cancer as reference, the odds ratios (95% confidence interval [CI]) of advanced stage of cancer were 2.20 (1.92-2.51) for tongue, 2.60 (2.28-2.97) for buccal, 2.68 (2.20-3.28) for floor of mouth, 2.96 (2.52-3.47) for hard palate, 6.04 (5.17-7.05) for gingiva, and 10.83 (9.20-12.74) for oropharynx. The estimated hazard ratios (95% CI) for oral cancer death increased from 1.48 (1.31-1.67) in buccal, 1.61 (1.43-1.82) in tongue, 1.68 (1.41-1.99) in floor of mouth, 1.79 (1.57-2.05) in gingiva, 1.97 (1.71-2.26) in hard palate, and 2.15 (1.89-2.45) in oropharynx. Conclusion Different anatomic sites had variations in advanced stage of and death from oral cancer and need vigilant surveillance.
Databáze: OpenAIRE
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