Brava and autologous fat transfer is a safe and effective breast augmentation alternative: results of a 6-year, 81-patient, prospective multicenter study
Autor: | Roger K. Khouri, Marita Eisenmann-Klein, Eva C. Gombos, Eufemiano Cardoso, Thomas J. Baker, Brian C. Cooley, Daniel F. Kacher |
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Rok vydání: | 2012 |
Předmět: |
Adult
medicine.medical_specialty Adolescent Mammaplasty Tissue Expansion Transplantation Autologous Autologous Fat Transfer Young Adult Medicine Humans Breast Prospective Studies Breast augmentation Tissue expander business.industry Graft Survival Tissue Expansion Devices Middle Aged Magnetic Resonance Imaging Surgery Treatment Outcome Multicenter study Adipose Tissue Female business Follow-Up Studies |
Zdroj: | Plastic and reconstructive surgery. 129(5) |
ISSN: | 1529-4242 |
Popis: | Breast augmentation by autologous fat transfer is an appealing alternative in need of scientific validation.In a prospective multicenter study, 81 women (age range, 17 to 63 years) wore the Brava device, a bra-like vacuum-based external tissue expander, for 4 weeks and then underwent autologous fat injection using 10 to 14 needle puncture sites into each breast in a three-dimensional fanning pattern (average, 277 ml volume injected per breast). Patients resumed Brava wear within 24 hours for 7 or more days. Pretreatment and posttreatment breast volumes were derived from three-dimensional volumetric reconstruction of magnetic resonance imaging scans, and outcomes were compared with a meta-analysis of six recent published reports on autologous fat transfer breast augmentation without expansion. Follow-up ranged from 12 months to 6 years (average, 3.7 years).Breast volume was unchanged between 3 and 6 months. Seventy-one of the treated women were compliant with Brava wear and had a mean augmentation volume at 12 months of 233 ml per breast compared with 134 ml per breast in published series without Brava (p0.00001). Graft survival was 82 ± 18 percent compared with 55 ± 18 percent without Brava (p0.00001). There was a strong linear correlation (R = 0.87) between pregrafting Brava expansion and the resultant breast augmentation. There were no suspicious breast masses or nodules. Magnetic resonance imaging recognized a 16 percent incidence of fat necrosis easily identified at 1-year mammographic evaluation.: The addition of Brava expansion before autologous fat grafting leads to significantly larger breast augmentations, with more fat graft placement, higher graft survival rates, and minimal graft necrosis or complications, demonstrating high safety and efficacy for the procedure.Therapeutic, IV. |
Databáze: | OpenAIRE |
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