NODULE INCEPTION Recruits the Lateral Root Developmental Program for Symbiotic Nodule Organogenesis in Medicago truncatula
| Autor: | Giles E. D. Oldroyd, Verônica A. Grieneisen, Wouter Kohlen, Katharina Schiessl, Jakub Luptak, Paul Bailey, Karunakaran Ramakrishnan, Tak Lee, Matthew D. Carpenter, Kirankumar S. Mysore, Jiangqi Wen, Sebastian E. Ahnert, Aaron Thomas, Ioannis Tamvakis, Jodi L. Stewart Lilley |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Organogenesis CYTOKININ RESPONSE FACTOR rhizobia Plant Root Nodulation Plant Roots General Biochemistry Genetics and Molecular Biology Article nitrogen Rhizobia 03 medical and health sciences chemistry.chemical_compound Organogenesis Plant 0302 clinical medicine Auxin NODULE INCEPTION Medicago truncatula Laboratorium voor Moleculaire Biologie Symbiosis Plant Proteins chemistry.chemical_classification endosymbiosis biology Endosymbiosis Lateral root fungi YUCCA food and beverages lateral root/nodule organogenesis biology.organism_classification Cell biology Pericycle 030104 developmental biology chemistry Cytokinin Laboratory of Molecular Biology General Agricultural and Biological Sciences LATERAL ORGAN BOUNDARIES DOMAIN auxin 030217 neurology & neurosurgery Transcription Factors |
| Zdroj: | Current Biology, 29(21), 3657-3668.e5 Current Biology Current Biology 29 (2019) 21 |
| ISSN: | 0960-9822 |
| DOI: | 10.1016/j.cub.2019.09.005 |
| Popis: | Summary To overcome nitrogen deficiencies in the soil, legumes enter symbioses with rhizobial bacteria that convert atmospheric nitrogen into ammonium. Rhizobia are accommodated as endosymbionts within lateral root organs called nodules that initiate from the inner layers of Medicago truncatula roots in response to rhizobial perception. In contrast, lateral roots emerge from predefined founder cells as an adaptive response to environmental stimuli, including water and nutrient availability. CYTOKININ RESPONSE 1 (CRE1)-mediated signaling in the pericycle and in the cortex is necessary and sufficient for nodulation, whereas cytokinin is antagonistic to lateral root development, with cre1 showing increased lateral root emergence and decreased nodulation. To better understand the relatedness between nodule and lateral root development, we undertook a comparative analysis of these two root developmental programs. Here, we demonstrate that despite differential induction, lateral roots and nodules share overlapping developmental programs, with mutants in LOB-DOMAIN PROTEIN 16 (LBD16) showing equivalent defects in nodule and lateral root initiation. The cytokinin-inducible transcription factor NODULE INCEPTION (NIN) allows induction of this program during nodulation through activation of LBD16 that promotes auxin biosynthesis via transcriptional induction of STYLISH (STY) and YUCCAs (YUC). We conclude that cytokinin facilitates local auxin accumulation through NIN promotion of LBD16, which activates a nodule developmental program overlapping with that induced during lateral root initiation. Graphical Abstract Highlights • Lateral roots and nodules show extensive overlap in organogenesis and transcription • Nodule and lateral root initiation converges at an auxin maximum and LBD16 • Cytokinin promotes auxin biosynthesis via NIN and LBD16 during nodule initiation To overcome growth-limiting nitrogen deficiency in soils, legumes host nitrogen-fixing bacteria in symbiotic root nodules. Schiessl et al. show that despite different environmental stimuli and organ function, nodule and lateral root initiation converges on a local accumulation of the plant hormone auxin and a set of auxin-responsive regulators. |
| Databáze: | OpenAIRE |
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