Cone-beam CT to assess bony fusion following anterior cervical interbody fusion
| Autor: | Jan Vandevenne, Leen Wijnen, J. Wuyts, Dieter Peuskens |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
Cone beam computed tomography cone-beam CT ACIF procedure fusion greyscale medicine.medical_treatment Bony fusion Dentistry Osseointegration 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine Humans Orthopedics and Sports Medicine Cone beam ct Fusion business.industry 030206 dentistry Prostheses and Implants Cone-Beam Computed Tomography Middle Aged medicine.anatomical_structure Spinal Fusion Intervertebral Disc Displacement Spinal fusion Bone Substitutes Cervical Vertebrae Surgery Nuclear medicine business Cervical vertebrae |
| Zdroj: | European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 25 |
| ISSN: | 1432-0932 |
| Popis: | Purpose Assessment of bony fusion following anterior cervical interbody fusion (ACIF) is usually done by plain film or CT. We present the first clinical application of Cone-Beam CT (CBCT) to evaluate bony fusion after ACIF. Methods A 56-year-old man with disc herniation at C6-C7 underwent ACIF surgery using a compressed nanocrystalline hydroxyapatite interbody device (nanOss-C, Pioneer Surgical Marquette, MI, USA) and a nanocrystalline hydroxyapatite bone graft filler (nanOss Bioactive, Pioneer Surgical Marquette, MI, USA). Imaging follow-up was performed by CBCT (NewTom 5G, QR Srl, Verona, Italy) at 1 day, 6 weeks, 3 and 9 months post-operatively. Two independent assessors quantitatively measured the greyscale changes of the bone graft filler and qualitatively evaluated the bony fusion process. Results Quantitative analysis of the images showed a steadily increasing matrix density of the bone graft filler over the 9 months follow-up, suggesting increasing calcification. Qualitative evaluation demonstrated different stages of the bone fusion process within the disc space around the cage, at the interface between cage and end-plates, and at the interface between bone graft filler and the endplates. Conclusions CBCT provides high-resolution cross-sectional imaging of the cervical spine after ACIF. For the first time, in vivo evaluation of the bone graft filler within the centre of the circumferentially radiodense cage and detailed cross-sectional evaluation of bone fusion was achieved. Confirmation of these promising outlooks of CBCT in a large cohort of ACIF patients is needed with regard to routine clinical application and evaluation of different interbody devices. Conflict of interest Jan Vandevenne and Leen Wijnen have no financial interest in RTI Surgical. Dieter Peuskens is a clinical investigator for RTI Surgical. The authors have no conflict of interest in this study |
| Databáze: | OpenAIRE |
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