Exogenous melatonin reduces somatic cell count of milk in Holstein cows
| Autor: | Jing Wang, Jingli Tao, Yukun Song, Jian-Min Shi, Jianhua Tian, Minghui Yang, Guoshi Liu, Zhiyuan Xu, Menglong Chai, Pengyun Ji, Kuanfeng Zhu |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Hydrocortisone 040301 veterinary sciences Injections Subcutaneous Serum albumin Mastitis Drug Administration Schedule Article 0403 veterinary science Melatonin Andrology 03 medical and health sciences chemistry.chemical_compound Immune system Lactate dehydrogenase medicine Animals Lactation Lymphocyte Count Lymphocytes Multidisciplinary biology L-Lactate Dehydrogenase Albumin food and beverages Alanine Transaminase Serum Albumin Bovine 04 agricultural and veterinary sciences medicine.disease Immunity Innate stomatognathic diseases Dairying 030104 developmental biology Milk Alanine transaminase chemistry Immunoglobulin M Immunoglobulin G biology.protein Cattle Female Somatic cell count medicine.drug |
| Zdroj: | Scientific Reports |
| ISSN: | 2045-2322 |
| Popis: | High somatic cell counts in milk caused by mastitis significantly influence the quality of milk and result in substantial annual economic loss. This study evaluated the beneficial effects of melatonin (MT) on milk somatic cell count (SCC) in cows. To examine the effects of melatonin on SCC, one hundred twenty cows were divided into four groups based on milk SCC. In each group, half of the cows were treated with melatonin (S.C.). Melatonin treatment significantly reduced milk SCC. To explore the potential mechanism, 20 cows with relatively high SCC were selected to evaluate the biochemical and immunological profiles of their blood after melatonin treatment. Treatment with MT significantly reduced SCC in milk, lowered serum cortisol concentrations and increased the levels of albumin, alanine transaminase and lactate dehydrogenase. Following treatment with MT, the concentration of IgG and IgM rose transiently then decreased significantly, similar to changes observed for white blood cells and lymphocytes. In conclusion, MT treatment improved the quality of milk by reducing SCC. This may be due to melatonin improving immune activity in cows. |
| Databáze: | OpenAIRE |
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