Body mass index and risk of pancreatic cancer in a Chinese population
| Autor: | Ai Zhen Jin, Kristin E. Anderson, Andrew O. Odegaard, Jian-Min Yuan, Woon-Puay Koh, Seema Untawale |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Male
Lifestyle Causes of Cancer Epidemiology lcsh:Medicine Global Health Body Mass Index Cohort Studies 0302 clinical medicine Clinical Epidemiology 030212 general & internal medicine lcsh:Science 2. Zero hunger Singapore Multidisciplinary Cancer Risk Factors Hazard ratio Middle Aged 3. Good health Oncology 030220 oncology & carcinogenesis Cohort Medicine Female Public Health Underweight medicine.symptom Cancer Epidemiology Cohort study Research Article medicine.medical_specialty China Clinical Research Design 03 medical and health sciences Pancreatic Cancer Internal medicine Pancreatic cancer Gastrointestinal Tumors medicine Humans Biology Proportional Hazards Models Gynecology Population Biology Proportional hazards model business.industry lcsh:R Cancers and Neoplasms nutritional and metabolic diseases medicine.disease Obesity Social Epidemiology Pancreatic Neoplasms lcsh:Q business Body mass index |
| Zdroj: | PLoS ONE, Vol 9, Iss 1, p e85149 (2014) PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | Few studies have examined the association between body mass index (BMI: kg/m(2)) and pancreatic cancer risk in Asian populations. We examined this relationship in 51,251 Chinese men and women aged 45-74 who enrolled between 1993 and 1998 in the population based, prospective Singapore Chinese Health Study. Data were collected through in-person interviews. By December 31, 2011, 194 cohort participants had developed pancreatic cancer. A Cox proportional hazards model was used to estimate hazard ratios (HR) and their 95% confidence intervals (95% CI). We hypothesized the association between BMI and pancreatic cancer risk may vary by smoking status (ever v. never) and there was evidence for this as the interaction between BMI and smoking status was significant (p = 0.018). Among ever smokers, being classified as underweight (BMI |
| Databáze: | OpenAIRE |
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