POSSIBILITIES OF MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING IN THE PERSONALIZATION OF SALVAGE RADIATION THERAPY IN PATIENTS WITH PROSTATE CANCER RECURRENCE
| Autor: | F. A. Kossov, P. V. Bulychkin, B. P. Olimov, V. O. Panov, S. I. Tkachev, Yu. V. Buydenok, N. L. Shimanovskiy, M. A. Shorikov, I. E. Tyurin, B. I. Dolgushin |
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| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_treatment
prostatic specific antigen R895-920 radiation therapy Gadobutrol Medical physics. Medical radiology. Nuclear medicine Prostate cancer dynamic magnetic resonance imaging with contrast enhancement medicine Prospective cohort study Gadoversetamide gadobutrol gadodiamide gadoversetamide medicine.diagnostic_test business.industry Prostatectomy Gadodiamide Magnetic resonance imaging General Medicine prostate cancer multiparametric magnetic resonance imaging medicine.disease Radiation therapy prostate cancer recurrence Nuclear medicine business medicine.drug |
| Zdroj: | Вестник рентгенологии и радиологии, Vol 99, Iss 2, Pp 91-100 (2018) |
| ISSN: | 0042-4676 |
| Popis: | Objective. To identify the possibility of multiparametrical magnetic resonance imaging (mpMRI) in the diagnosis of clinical recurrence of prostate cancer, with the aim of optimizing salvage radiation therapy (SLT). Material and methods. In this prospective study, the results of 89 patients with marker relapse (PSA) of prostate cancer (PCa) after radical prostatectomy was examined. mpMRI of the pelvis was performed before the SLT and 6 months later. Separately, in 44 patients, the data of dynamic contrast enhancement (DCE) with different contrast agents (gadobutrol, gadodiamide and gadoversetamide) were analyzed. Results . According to the model of multiple linear regression, the area of the substrate of clinical recurrence is statistically significantly correlated with the PSA level (R=0.74, p |
| Databáze: | OpenAIRE |
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