| Autor: |
Samuel H. Wilson, Padmini S. Kedar, Natalie R. Gassman, Rajendra Prasad, Donna F. Stefanick, Julie K. Horton |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1541-7786.22513761 |
| Popis: |
PDF file - 422KB, S1. Cell survival as measured by a clonogenic assay. S2. BRCT I domain of XRCC1. S3. Characterization of cell lines by western blotting. S4. Characterization of full-length wild-type XRCC1 and L360R mutant XRCC1 mouse proteins. S5. Inhibitory effect of olaparib (O) or veliparib (V) (10 mM) on PAR accumulation in MMS-treated (10 mM for 20 min at 4 degrees C) wild-type (red) and pol beta null cells (gray). S6. Effect of PARPi on sensitivity of wild-type (16.3, closed red symbols) and pol beta null (19.4, open black symbols) cells to MMS. S7. Sensitivity of pol beta- and XRCC1-deficient cell lines to olaparib and veliparib. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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