The Human Body’s Own Language to be Considered for Safe and Effective Neurostimulation
| Autor: | Safiye Bilgin, Metin Tulgar, Ayhan Yildirim |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Quality of life
medicine.medical_specialty Tulgar implants Neurology genetic structures medicine.medical_treatment Alternative medicine Epilepsy Quality of life (healthcare) Physical medicine and rehabilitation Seizures SAFER Medicine Neurostimulation Original Research business.industry Human body Heart breath and position mode of stimulation medicine.disease Neurology (clinical) business Neuroscience Vagus nerve stimulation |
| Zdroj: | Neurology and Therapy |
| ISSN: | 2193-6536 2193-8253 |
| Popis: | Introduction The general objective of this study was to provide an improved software for safer and more effective neurostimulation therapy. Materials and Methods Tulgar implants, employing combined modulation of stimulation synchronized with heart rate, breathing frequency, and position of the patient (HBP), were applied as vagus nerve stimulation (VNS) for the management of refractory epilepsy in 105 patients who were followed up for 1 year. Results Fifty-nine out of 105 (56.19%) patients were seizure free, 34 (32.38%) patients had partial improvement in quality of life with a decrease in intensity and frequency of the seizures, and 12 (11.43%) patients did not respond to stimulation. Discussion Other similar studies, undertaken with non-Tulgar equipment, reported a 10% full recovery, 60% partial improvement in quality of life, and 30% zero response. Comparisons of these results reveal an approximate fivefold increase in seizure freedom, and threefold decrease in the number of nonresponsive patients. Conclusions The findings of the present study imply that HBP-modulated mode of stimulation could be safer and more effective in neurostimulation, at least in VNS. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|