Efficacy of Two Triple Eradication Regimens in Children with Helicobacter pylori Infection
| Autor: | Joo Young Jang, Jungi Choi, Kyung Mo Kim, Hwa Young Park, Joon Sung Kim, Yon Ho Choe |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Adolescent macromolecular substances Helicobacter pylori Treatment Outcome Child Gastroenterology Bismuth subsalicylate Helicobacter Infections Clarithromycin Internal medicine Metronidazole bismuth subsalicylate medicine Organometallic Compounds Humans Child Omeprazole Retrospective Studies biology Helicobacter pylori business.industry food and beverages Amoxicillin Retrospective cohort study General Medicine biology.organism_classification bacterial infections and mycoses Salicylates Anti-Bacterial Agents Regimen Drug Combinations Treatment Outcome Child Preschool Immunology Original Article Female business Bismuth medicine.drug |
| Zdroj: | Journal of Korean Medical Science |
| ISSN: | 1598-6357 1011-8934 |
| Popis: | Triple therapy with bismuth subsalicylate, amoxicillin, metronidazole (BAM) or with omeprazole, amoxicillin, clarithromycin (OAC) has been commonly used for the eradication of Helicobacter pylori infection. We compared the efficacy of these triple therapies in children with H. pylori infection. We retrospectively analyzed results in 233 children with H. pylori infection and treated with OAC (n=141) or BAM (n=92). Overall eradication rates of triple therapy with OAC and BAM were 74% and 85%, respectively, which showed no statistical difference. Our study showed that the triple therapy with BAM was more effective for the first-line eradication of H. pylori infection in Korean children, but has no statistical difference with OAC regimen. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|