A universal split spinach aptamer (USSA) for nucleic acid analysis and DNA computation

Autor:	Nanami Kikuchi, Dmitry M. Kolpashchikov
Rok vydání:	2017
Předmět:	Analyte Nucleic acid quantitation Aptamer 010402 general chemistry 01 natural sciences Catalysis chemistry.chemical_compound Computers Molecular Materials Chemistry biology Base Sequence 010405 organic chemistry fungi Metals and Alloys food and beverages RNA General Chemistry DNA Aptamers Nucleotide Highly selective biology.organism_classification 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials Biochemistry chemistry Ceramics and Composites Nucleic acid Spinach
Zdroj:	Chemical communications (Cambridge, England). 53(36)
ISSN:	1364-548X
Popis:	We demonstrate how a single universal spinach aptamer (USSA) probe can be used to detect multiple (potentially any) nucleic acid sequences. USSA can be used for cost-efficient and highly selective analysis of even folded DNA and RNA analytes, as well as for the readout of outputs of DNA logic circuits.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e717ee94c44f86ca4e4e2eea2e1f17 https://pubmed.ncbi.nlm.nih.gov/28425510 Zobrazit plný text záznamu