Evaluation for West Nile Virus (WNV) RNA in urine of patients within 5 months of WNV infection

Autor: Katherine B Gibney, Jamie Feld, J. Erin Staples, Tricia Wadleigh, Andrean M. Bunko Patterson, Steven Baty, Marc Fischer, Jennifer A. Lehman, C. Thomas Nugent, Robert S. Lanciotti, Craig Levy
Rok vydání: 2012
Předmět:
Zdroj: The Journal of infectious diseases. 205(9)
ISSN: 1537-6613
Popis: West Nile virus (WNV) causes an acute infection that is usually cleared by an effective immune response after several days of viremia. However, a recent study detected WNV RNA in the urine of 5 of 25 persons (20%) tested several years after their initial acute WNV disease. We evaluated an established cohort of 40 persons >6 years after initial infection with WNV. Urine collected from all participants tested negative for WNV RNA by reverse-transcription polymerase chain reaction and transcription-mediated amplification. Prospective studies are needed to determine if and for how long WNV persists in urine following WNV disease.
Databáze: OpenAIRE