A randomised clinical trial comparing 2% econazole and 5% natamycin for the treatment of fungal keratitis
| Autor: | Rajesh K John, Prajna Lalitha, Muthiah Srinivasan, Namperumalsamy Venkatesh Prajna, Praveen K Nirmalan |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Antifungal Agents Econazole Adolescent Natamycin Keratitis law.invention Clinical Science - Extended Reports Cellular and Molecular Neuroscience Randomized controlled trial law Internal medicine Ophthalmology medicine Humans Fungal keratitis Child Aged Antibacterial agent Aged 80 and over business.industry Middle Aged Eye infection medicine.disease Sensory Systems Clinical trial Treatment Outcome Female business Eye Infections Fungal Follow-Up Studies medicine.drug |
| Zdroj: | British Journal of Ophthalmology. 87:1235-1237 |
| ISSN: | 0007-1161 |
| DOI: | 10.1136/bjo.87.10.1235 |
| Popis: | Aim: To compare 2% econazole and 5% natamycin in the management of fungal keratitis. Methods: A randomised clinical trial was performed using 2% econazole or 5% natamycin as the two treatment arms on patients presenting with culture positive fungal keratitis to the cornea service at Aravind Eye Care System, Madurai, India. Results: 116 patients were recruited, and 112 continued in the study. There were no significant differences between the two arms at baseline or for success (defined as a healed or healing ulcer) at final visit (p = 0.79). Conclusions: 2% Econazole appears to be as effective as 5% natamycin for the management of fungal keratitis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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