Multi-institutional evaluation of knowledge-based planning performance of volumetric modulated arc therapy (VMAT) for head and neck cancer
| Autor: | Tatsuya Kamima, Hajime Monzen, Mikoto Tamura, Kazuki Ishikawa, Yoshihiro Ueda, Yumiko Shimizu, Junichi Fukunaga |
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| Rok vydání: | 2019 |
| Předmět: |
Organs at Risk
medicine.medical_specialty Knowledge based planning Biophysics Planning target volume General Physics and Astronomy 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine stomatognathic system Oropharynx Cancers medicine Humans Radiology Nuclear Medicine and imaging Medical physics business.industry Radiotherapy Planning Computer-Assisted Head and neck cancer Radiotherapy Dosage General Medicine medicine.disease Volumetric modulated arc therapy Parotid gland medicine.anatomical_structure Head and Neck Neoplasms 030220 oncology & carcinogenesis Radiotherapy Intensity-Modulated business |
| Zdroj: | Physica Medica. 64:174-181 |
| ISSN: | 1120-1797 |
| DOI: | 10.1016/j.ejmp.2019.07.004 |
| Popis: | Purpose The aim of this study was to investigate whether additional manual objectives are necessary for the RapidPlan (RP) with a single optimization. We conducted multi-institutional comparisons of plan quality for head and neck cancer (HNC) using the models created at each institute. Methods The ability of RP to produce acceptable plans for dose requirements was evaluated in two types of oropharynx cancers at five institutes in Japan. Volumetric modulated arc therapy plans created without (RP plan) and with additional manual objectives (M-RP plan) were compared in terms of planning target volume (PTV), brainstem, spinal cord and parotid glands in dosimetric parameters. Results There were no major dosimetric PTV differences between RP and M-RP plans. For the brainstem and spinal cord in the RP plans, only 40% and 30% of the plans achieved the dose requirements, while the M-RP plans with upper objective added to volume 0% at all institutes achieved them for 90% of the plans. For the L-parotid gland, there was no difference in the RP and M-RP plans (both were 40%) in achieving the acceptable criteria. For the R-parotid gland, 60% and 80% of the RP and M-RP plans achieved the constraint criteria, and in terms of the achievement rate, the RP plans were relatively high. Conclusions M-RP plans did not require reoptimization; only an upper objective was needed for the brainstem and spinal cord, while the parotid gland dose was reduced in both RP plans with the auto generated line objectives alone. |
| Databáze: | OpenAIRE |
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