Kikuchi-Fujimoto disease presenting in a patient with SARS-CoV-2: a case report
| Autor: | Samuel D. Racette, Borislav A. Alexiev, Akihiro J. Matsuoka, Senthil Balasubramanian, Kaitlin Lima, Lawrence J. Jennings, Ajay Bhasin, Michael Angarone |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Lymph node biopsy Lymphadenopathy Folliculitis Case Report Infectious and parasitic diseases RC109-216 Disease Diagnosis Differential Cervical lymphadenopathy Kikuchi-Fujimoto Syndrome medicine Humans music Histiocytic Necrotizing Lymphadenitis music.instrument medicine.diagnostic_test business.industry SARS-CoV-2 COVID-19 Emergency department medicine.disease Dermatology Follicular hyperplasia Infectious Diseases Chills Lymph Nodes Differential diagnosis medicine.symptom business |
| Zdroj: | BMC Infectious Diseases BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-4 (2021) |
| ISSN: | 1471-2334 |
| Popis: | Background We present a yet to be described association of SARS-CoV-2 infection with Kikuchi-Fujimoto disease. Case presentation A 32-year-old physician with history of SARS-CoV-2 infection presented to the emergency department with 2 weeks of fever, chills, and right sided cervical lymphadenopathy. He was treated empirically for presumed folliculitis with worsening of symptoms leading to repeat presentation to the emergency department. Extensive workup was unrevealing of an infectious cause and needle biopsy of the lesion was unrevealing. An excisional lymph node biopsy revealed follicular hyperplasia with necrotic foci showing abundance of histiocytes at the edge of necrosis with CD8 predominance of T-cells. Final diagnosis was deemed to be Kikuchi-Fujimoto disease. Antibiotic therapy was discontinued, and the patient’s symptoms resolved with steroid therapy and expectant management. Conclusions This is the first report of a patient developing Kikuchi-Fujimoto disease following SARS-CoV-2 infection. Clinicians should be aware of Kikuchi-Fujimoto disease as a possibility when approaching patients with hyper-inflammatory states who present with cervical lymphadenopathy. |
| Databáze: | OpenAIRE |
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