Blood screening for non-A, non-B hepatitis by hepatitis C virus antibody assay
| Autor: | Q L Choo, Shu Kikuchi, Y Tanaka, Michael Houghton, Tohru Katayama, George Kuo, Tatsuo Miyamura, Izumu Saito |
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| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Blood transfusion Hepatitis Viral Human medicine.medical_treatment Hepatitis C virus Immunology Radioimmunoassay Biology Antibodies Viral medicine.disease_cause Virus Antigen Hepatitis Viruses medicine Humans Mass Screening Immunology and Allergy Mass screening Aged Hepatitis Hematology Middle Aged medicine.disease Hepatitis C Virology Recombinant Proteins digestive system diseases biology.protein Female Antibody |
| Zdroj: | Transfusion. 30:374-376 |
| ISSN: | 1537-2995 0041-1132 |
| DOI: | 10.1046/j.1537-2995.1990.30490273448.x |
| Popis: | Hepatitis C virus (HCV) antibody was detected in 1499 donor sera by radioimmunoassay using an antigen expressed in yeast from a cDNA clone of the HCV genome. Eighteen samples over 4200 counts per minute (cpm) were considered to contain infectious HCV because these recipients developed typical posttransfusion non-A, non-B hepatitis after transfusion. The antibody-positive sera were all within the normal range of ALT levels. This assay system is thus useful for the screening for blood transfusion. |
| Databáze: | OpenAIRE |
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