Clinical Frailty Scale classes are independently associated with 6-month mortality for patients after acute myocardial infarction
| Autor: | Niklas Ekerstad, Dariush Javadzadeh, Karen P Alexander, Olle Bergström, Lars Eurenius, Mats Fredrikson, Gudny Gudnadottir, Claes Held, Karin Hellström Ängerud, Radwan Jahjah, Tomas Jernberg, Ewa Mattsson, Kjell Melander, Linda Mellbin, Monica Ohlsson, Annica Ravn-Fischer, Lars Svennberg, Troels Yndigegn, Joakim Alfredsson |
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| Rok vydání: | 2021 |
| Předmět: |
Kardiologi
Frailty Omvårdnad Frail Elderly Myocardial Infarction General Medicine Nursing Critical Care and Intensive Care Medicine Prognosis Risk prediction Myocardial infarction Clinical Frailty Scale Mortality Humans Cardiac and Cardiovascular Systems Prospective Studies Cardiology and Cardiovascular Medicine Aged Retrospective Studies |
| Zdroj: | European heart journal. Acute cardiovascular care. 11(2) |
| ISSN: | 2048-8734 |
| Popis: | Aims Data on the prognostic value of frailty to guide clinical decision-making for patients with myocardial infarction (MI) are scarce. To analyse the association between frailty classification, treatment patterns, in-hospital outcomes, and 6-month mortality in a large population of patients with MI. Methods and results An observational, multicentre study with a retrospective analysis of prospectively collected data using the SWEDEHEART registry. In total, 3381 MI patients with a level of frailty assessed using the Clinical Frailty Scale (CFS-9) were included. Of these patients, 2509 (74.2%) were classified as non-vulnerable non-frail (CFS 1–3), 446 (13.2%) were vulnerable non-frail (CFS 4), and 426 (12.6%) were frail (CFS 5–9). Frailty and non-frail vulnerability were associated with worse in-hospital outcomes compared with non-frailty, i.e. higher rates of mortality (13.4% vs. 4.0% vs. 1.8%), cardiogenic shock (4.7% vs. 2.5% vs. 1.9%), and major bleeding (4.5% vs. 2.7% vs. 1.1%) (all P Conclusion Frailty assessed with the CFS was independently and strongly associated with all-cause 6-month mortality, also after comprehensive adjustment for baseline differences in other risk factors. Similarly, non-frail vulnerability was independently associated with higher mortality compared with those with preserved functional ability. |
| Databáze: | OpenAIRE |
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